Galantos HEParanase Assay: a convenient screening and research tool Galantos Genetics GmbH provides a proprietary heparanase assay which rapidly produces high quality results and can be used for heparanase inhibitor screening and for monitoring of heparanase enzyme activity in tissues or liquids.

Assay Features :

Important Applications and Research Areas

Assay principle

The proprietary GALANTOS heparanase assay is based on the high affinity binding of a labeled heparan sulfate (HS) substrate to an immobilized heparan sulfate bin-ding protein (HS-BP). Cleavage of the substrate HS by the enzyme heparanase abolishes its binding to the HS-BP, that was immobilized to the surface of a microplate.

Assay accuracy

CV values (intra-assay) are in the range of 2-3 % for manually performed assays and < 2 % for automated assays. more >>